[Frontiers in Bioscience 10, 1229-1238 May 1, 2005] 1229 CYCLIC GMP-DEPENDENT PROTEIN KINASES IN PROTOZOA

نویسندگان

  • David A. Baker
  • Wensheng Deng
  • Michael Smith
چکیده

1. Abstract 2. Introduction 3. A subgroup of protozoa possess PKGs with more than two cGMP-binding sites 4. Functional analysis of individual cGMP-binding sites of apicomplexan PKGs 5. Potential autoinhibitory N-terminal sequences 6. Autophosphorylation of PKG isoforms 7. Biochemical properties of apicomplexan PKGs 8. Apicomplexan parasite PKGs as specific drug targets 9. Biological function of PKGs in protozoa 10. Function of PKG isoforms in other non-mammalian systems 11. Summary 12. Acknowledgement 13. References

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تاریخ انتشار 2005